Broccoli Sources and Readings


Literary Reviews and Readings:

James D. Brook, Vincent G. Paton and Genevieve Vidanes. Potent induction of phase-2-enzymes in human prostate cells by sulforaphane.. Cancer Epidemiology Biomarkers and Prevention, Vol. 10, 949-954, September 2001

Kenji Niwa et al. Preventive Effects of Indole-3-Carbinol on Endometrial Carcinogenesis in Mice. Japanese Journal of Reproductive Endocrinology, 2004

Jed W. Fahey,Dagger, Xavier Haristoy, Patrick M. Dolan, Thomas W. Kensler, Isabelle Scholtus, Katherine K. Stephenson, Paul Talalay and Alain Lozniewski . Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pylori and prevents benzo-a-pyrene-induced stomach tumors. PNAS,May 28, 2002;99(11):7610-7615

Matthew A. Wallig, Kathleen M. Heinz-Taheny, Donna L. Epps and Tamara Gossman. Synergy among Phytochemicals within Crucifers: Does It Translate into Chemoprotection? Journal of Nutrition 135:2972S-2977S, December 2005

Bell MC, Crowley-Nowick P, Bradlow HL, et al. Placebo-controlled trial of indole-3-carbinol in the treatment of CIN. Gynecol Oncol. 2000;78:123-129.

Brennan P, Hsu CC, Moullan N, et al. Effect of cruciferous vegetables on lung cancer in patients stratified by genetic status: a mendelian randomisation approach. Lancet.2005;366:1558-1560.

Cao G, Booth SL, Sadowski JA, Prior RL. Increases in human plasma antioxidant capacity after consumption of controlled diets high in fruit and vegetables. Am J Clin Nutr. 1998;68:1081-1087.

Cover CM, Hsieh SJ, Tran SH, et al. Indole-3-carbinol inhibits the expression of cyclin-dependent kinase-6 and induces a G1cell cycle arrest of human breast cancer cells independent of estrogen receptor signaling. J Biol Chem. 1998;273:3838-3847.

Fahey JW, Zhang Y, Talalay P. Broccoli sprouts: an exceptionally rich source of inducers of enzymes that protect against chemical carcinogens. Proc Natl Acad Sci USA.1997;94:10367-10372.

Michaud DS, Pietinen P, Taylor PR, Virtanen M, Virtamo J, Albanes D. Intakes of fruits and vegetables, carotenoids and vitamins A, E, C in relation to the risk of bladder cancer in the ATBC cohort study. Br J Cancer. 2002;87:960-965.

Michaud DS, Spiegelman D, Clinton SK, Rimm EB, Willett WC, Giovannucci EL. Fruit and vegetable intake and incidence of bladder cancer in a male prospective cohort. J Natl Cancer Inst. 1999;91:605-613.

Nestle M. Broccoli sprouts in cancer prevention. Nutr Rev. 1998;56:127-130.

Parnaud G, Li P, Cassar G, et al. Mechanism of sulforaphane-induced cell cycle arrest and apoptosis in human colon cancer cells. Nutr Cancer. 2004;48:198-206.

Parnaud G, Li P, Cassar G, Rouimi P, Tulliez J, Combaret L, Gamet-Payrastre L. Mechanism of sulforaphane-induced cell cycle arrest and apoptosis in human colon cancer cells. Nutr Cancer. 2004;48:198-206.

PDRhealth. Indole-3-Carbinol. Accessed at: on Accessed June 10, 2008.

PDRhealth. Sulforaphane. Accessed at: on June 12, 2007. Content no longer available.

Shapiro TA, Fahey JW, Wade KL, Stephenson KK, Talalay P. Human metabolism and excretion of cancer chemoprotective glucosinolates and isothiocyanates of cruciferous vegetables. Cancer Epidemiol Biomarkers Prev. 1998;7:1091-1100.

Shapiro TA, Fahey JW, Dinkova-Kostova AT, et al. Safety, tolerance, and metabolism of broccoli sprout glucosinolates and isothiocyanates: a clinical phase I study. Nutrition & Cancer. 2006;55:53-62.

Singh SV, Srivastava SK, Choi S, et al. Sulforaphane-induced cell death in human prostate cancer cells is initiated by reactive oxygen species. J Biol Chem. 2005;280:19911-19924.

Slattery ML, Benson J, Curtin K, Ma KN, Schaeffer D, Potter JD. Carotenoids and colon cancer. Am J Clin Nutr. 2000;71:575-582.

Tang L, Zhang Y, Jobson HE, et al. Potent activation of mitochondria-mediated apoptosis and arrest in S and M phases of cancer cells by a broccoli sprout extract. Molecular Cancer Therapeutics.2006;5:935-944.

3 responses to “Broccoli Sources and Readings

  1. Pingback: Sauteed Kale with Onion and Garlic « THE URBAN CLINIC·

  2. Hello! I know this is somewhat off topic but I was wondering if you knew where I could locate a captcha plugin for my comment form? I’m using the same blog platform as yours and I’m having difficulty finding one? Thanks a lot!

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